In short. Descent carries most of the appearance, volume loss deepens how the groove reads, bone change reverses for nobody and skin laxity is the part you can influence.

Key points

  • Volume loss responds best.
  • Skin quality responds partially and slowly to care and sun protection.
  • Descent responds to an operation, and not completely.

Patients are usually told that the fold comes from loss of collagen, which explains very little. Four changes produce it. They are not equally important, and they are not equally changeable, so ranking them honestly is more useful than any single explanation: it tells you which part of what you see is worth addressing and which part has to be accepted.

Midface descent: the largest contributor

The cheek pad moves down and forward over the upper lip. In an adult face this carries most of the appearance, and it is why a fold deepens over years rather than appearing at once. Descent is also the change that material placed in the groove cannot correct, because filling the groove does not put the cheek back where it was. It is the one change that an operation repositions directly.

Volume loss: what deepens the read

The deep compartments that hold the cheek forward thin out, so the midface loses projection and the fold beside it reads as a deeper groove in a face that has not moved far. Volume loss is genuinely treatable, and deep support placed to restore the cheek is the rung that addresses it. What support cannot do is lift what has already dropped.

The four, ranked by what can be changed

Volume loss responds best. Skin quality responds partially and slowly to care and sun protection. Descent responds to an operation, and not completely. Bone remodelling responds to nothing available. That order is the honest basis for deciding what to do, and for deciding what to stop expecting.

Bone remodelling: slow, real, not reversible

The midface skeleton changes over decades. The opening of the nose widens, the upper jaw loses projection, and the platform the cheek rests on moves backward. No injection reaches this and no lift reverses it. It is worth knowing because it explains a fold that deepens in a face whose skin and weight have not changed at all.

Skin laxity: the part you can influence

Skin that has lost its elastic recoil stays where the cheek has pushed it rather than springing back. Sun exposure and smoking accelerate that loss. Skin care and daily sun protection change how sharp the fold looks and how much of the surface is contributing, and neither moves the junction. A plan built only on them is built on the smallest of the four changes.

Claims worth checking

  • A cream described as lifting the cheek, when the cheek has descended.
  • A fold described as removable, when it is a junction every face has.
  • A plan that never mentions the position of the cheek at all.

How each of these is told apart in an examination is described in the assessment guide. The reason treatment aimed at the groove itself goes wrong is explained in why a flat fill disappoints, and where the causes amount to normal anatomy, the case for no treatment is set out in when nothing needs doing.

Related reading

Frequently asked questions

Which of these causes can actually be changed?

Volume loss responds best, and deep support placed for it is a real treatment. Skin quality responds partially and slowly to care and daily sun protection. Descent responds only to an operation, and not completely. Bone remodelling responds to nothing currently available. Ranking them that way is more useful than a single explanation, because it tells you what to stop expecting.

Does having a fold mean my face has aged badly?

No. A fold is present in childhood and is part of how a face is built. Several ethnic facial patterns show a prominent fold in young faces that have not descended at all, and a strong smile muscle deepens it in a laugh at any age. A fold becomes a marker of ageing when the cheek has moved, not simply because the fold is visible.

Why does the fold look different in different photographs?

Because a camera records shadow more starkly than the eye does. Light from directly in front removes the shadow that gives the groove its depth, while light from above deepens it. Two photographs taken within an hour can look like two different faces, which is why a single picture is a record of one moment in one light rather than evidence about what has changed.

Risks & Limitations

  • Filling the fold itself rather than the cheek widens the midface, and correcting that is harder than the original complaint.
  • Material placed deep in this region can enter a vessel and obstruct the blood supply to skin, which is why the area is treated with more caution than most.
  • Support placed to restore the cheek changes the midface without restoring a cheek that has genuinely descended.
  • Thread lifting is temporary by design, and no rung on the ladder removes the fold itself.

When to Seek Care

  • A fold that appeared over weeks, or is present on one side only.
  • Weakness on one side of the face, numbness in the cheek or lip, drooling, or difficulty closing an eye — seek urgent care.
  • Skin in a treated area that turns pale, grey, mottled or blistered, or severe pain after an injection.
  • A lump that can be felt in the cheek or lip, or swelling with pain, redness or warmth.

References & Further Reading

  • American Society of Plastic Surgeons (ASPS) — procedure and safety guidance
  • National Institute for Health and Care Excellence (NICE, UK) — relevant guidance
  • Cochrane Library — systematic reviews
  • Chinese Medical Association Plastic Surgery Branch — clinical guidance

Medically reviewed by Tongchun Mao, MD (毛彤春), Deputy Director & Head of Aesthetic Surgery. Last reviewed: 19 September 2026.

This page is patient education, not medical advice, and it does not cite individual studies. Discuss your own case with a qualified clinician. To arrange an assessment at Chongqing West District Hospital, see Contact & Consultation.